Insulin receptor expression by human prostate cancers
نویسندگان
چکیده
منابع مشابه
Receptor Type II in Rat Prostate Cancers
To identify methylation-silenced genes in prostate cancers, a microarray analysis for genes up-regulated by treatment with a demethylating agent, 5-aza-2¶-deoxycytidine, was performed using three rat prostate cancer cell lines. Eight genes (Aebp1, Dysf, Gas6, LOC361288, Nnat, Ocm, RGD1308119 , and Tgfbr2) were re-expressed at 16-fold or more, and their promoter CpG islands were shown to be dens...
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There are few options for treating hormone-refractory prostate cancer (PC). Various studies indicate that luteinizing hormone-releasing hormone (LHRH) agonists may have a direct inhibitory effect on prostate tumors mediated by specific LHRH receptors. One study evaluated LHRH receptors in hormone-dependent PC tissue, but no data have thus far been obtained on the presence of LHRH receptors in b...
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Responses to androgen vary widely among prostate cancers and prostatic carcinoma cell lines. We have explored the basis for this heteroge neity by examining the levels of androgen receptor expression in a prostate carcinoma cell line (LNCaP) that expresses the androgen recep tor and two prostate carcinoma cell lines that do not contain detectable androgen receptor. We find that while the LNCaP ...
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ژورنال
عنوان ژورنال: The Prostate
سال: 2009
ISSN: 0270-4137,1097-0045
DOI: 10.1002/pros.20852